(Dan Itkis) Thought I'd through this out there:

(Paul Greenberg) joined too 

Collaboration

within and outside the firm.  Wikis are gaining momentum.

Usability Improvements

AJAX, emphasis on processes rather than data, various areas targeted to how people within that department think and work

Integration

… with 3^rd party systems, in-house systems

Development Platform

Salesforce’s APEX.. great idea.. can they pull it off?

Verticalization

Among others within the SMB market where IT and training resources are scarce or not available but also increasingly in the largest enterprises - especially those where

the buy is emotional (retail) or the buy-in (financial services) is emotional

Social Networking

…especially for service industries, referrals and networking are at the heart of their marketing strategies

Customer Centricity

Customer should really be in charge of who sees their information and what kind of goods and services they are in the market for

Prosumer Behaviors

The inculcation of consumer behaviors into professional environments; the importance of style as a choice when choosing products and services